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临床试验/NCT07089316
NCT07089316已完成不适用

Preoperative MRI and Radiographic Parameters Are Associated With Medial Meniscus Posterior Root Tears and Predict Mid-Term Clinical and Radiographic Outcomes After Repair

Karadeniz Technical University1 个研究点 分布在 1 个国家目标入组 128 人开始时间: 2025年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
128
试验地点
1
主要终点
Medial Tibial Slope

研究概览

简要总结

This retrospective observational study aims to investigate whether specific preoperative magnetic resonance imaging (MRI) and radiographic parameters are associated with medial meniscus posterior root tears (MMPRT), and whether these parameters have predictive value for mid-term clinical and radiographic outcomes after arthroscopic repair.

Patients with arthroscopically confirmed MMPRT treated between 2020 and 2024 are evaluated based on their preoperative MRI and standing knee radiographs. Imaging parameters of interest include medial tibial slope, meniscal extrusion, tibial plateau depth, posterior root angle, and intercondylar notch morphology. Clinical outcomes are assessed using standardized scoring systems. The study aims to identify imaging-based anatomical risk factors to improve diagnosis, patient selection, and prognosis following MMPRT repair.

详细描述

This retrospective observational study investigates the role of specific preoperative MRI and radiographic parameters in the diagnosis and prognosis of medial meniscus posterior root tears (MMPRT). Conducted at the Department of Orthopaedics and Traumatology, Karadeniz Technical University Farabi Hospital, the study aims to clarify whether morphologic imaging findings-such as medial tibial slope, meniscal extrusion, tibial plateau depth, posterior root angle, and intercondylar notch morphology-are associated with the presence of MMPRT and influence postoperative outcomes following arthroscopic repair.

All imaging measurements were performed using standardized techniques on MRI and radiographs obtained prior to surgery. Parameters were assessed by two independent orthopedic surgeons on separate occasions to evaluate interobserver reliability. A matched control group of patients without meniscal pathology was formed to strengthen the comparative analysis and support the identification of risk factors.

By analyzing a wide range of anatomic features on imaging, this study seeks to enhance early diagnostic accuracy, improve patient selection for surgical repair, and refine prognostic counseling. The findings are expected to contribute to the development of objective, imaging-based indicators that can guide clinical decision-making and predict mid-term clinical and radiographic outcomes after MMPRT repair.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Patients aged 18 years or older
  • •Arthroscopically confirmed medial meniscus posterior root tear (MMPRT) diagnosis
  • •Availability of preoperative knee MRI and standing long-leg radiographs
  • •Minimum 24-month clinical and radiographic follow-up

排除标准

  • •Lateral meniscus tear
  • •Kellgren-Lawrence grade 3 or higher knee osteoarthritis
  • •Advanced ligament injuries
  • •History of previous knee surgery, osteotomy, or arthroplasty
  • •Poor imaging quality
  • •Mechanical axis deformities (varus or valgus alignment)
  • •Follow-up period less than 24 months

研究组 & 干预措施

MMPRT Patients

Patients with medial meniscus posterior root tears undergoing arthroscopic repair.

Control Patients

Patients without meniscus tears, matched by age, BMI, and mechanical axis.

结局指标

主要结局

Medial Tibial Slope

时间窗: Preoperative MRI assessment

Measured in degrees (°) on sagittal MRI. It is the angle between the tangent to the medial tibial plateau and the anatomical axis of the proximal tibia, drawn using a line connecting the anterior and posterior cortices of the plateau.

Medial Meniscus Extrusion

时间窗: Preoperative MRI assessment

Measured in millimeters (mm) on coronal MRI. Defined as the distance from the outer margin of the medial meniscus to the edge of the tibial plateau

Tibial Plateau Depth

时间窗: Preoperative MRI assessment

Measured in millimeters (mm) on sagittal MRI. It is the perpendicular depth from the deepest point of the medial tibial plateau concavity to a reference line connecting the anterior and posterior cortical rims.

Intercondylar Notch Width

时间窗: Preoperative MRI assessment

Measured in millimeters (mm) on axial MRI images. Width of the intercondylar notch at the level of the popliteal groove.

Intercondylar Distance

时间窗: Preoperative MRI assessment

Measured in millimeters (mm) on axial MRI. The distance between the outer surfaces of the medial and lateral femoral condyles at the level of the intercondylar notch.

Medial Femoral Condyle Angle

时间窗: Preoperative MRI assessment

Measured in degrees (°) on sagittal MRI. It is the angle between the femoral anatomical axis and the curvature of the medial femoral condyle.

Notch Width Index (ICNW/ICD Ratio)

时间窗: Preoperative MRI assessment

A unitless ratio obtained by dividing the intercondylar notch width by the intercondylar distance on axial MRI at the level of the popliteal groove.

Notch Shape

时间窗: Preoperative MRI assessment

Morphological classification based on axial MRI. The intercondylar notch is categorized into A-type, U-type, or W-type based on its geometric configuration.

Presence of Osteophyte (Spur)

时间窗: Preoperative MRI assessment

Binary variable (Yes/No) indicating the presence of an osteophyte at the intercondylar notch on axial or sagittal MRI.

Medial Femoral Condyle Width (MFCW)

时间窗: Preoperative MRI assessment

Measured in millimeters (mm) on coronal MRI. The width of the medial tibial plateau at its maximum span.

Medial Tibial Plateau Width (MTPW)

时间窗: Preoperative MRI assessment

Measured in millimeters (mm) on coronal MRI. The width of the medial tibial plateau at its maximum span.

MFCW/MTPW Ratio

时间窗: Preoperative MRI assessment

Unitless ratio calculated by dividing medial femoral condyle width (MFCW) by medial tibial plateau width (MTPW) on coronal MRI.

Medial Femoral Condyle Distal Offset Distance

时间窗: Preoperative MRI

Measured in millimeters (mm) on sagittal MRI at the level of the medial femoral condyle midpoint (defined on coronal MRI) as the perpendicular distance from the intercondylar axis to the most distal point of the condyle.

Medial Femoral Condyle Posterior Offset Distance

时间窗: Preoperative MRI

Measured in millimeters (mm) on the same sagittal MRI slice as the distal offset, defined as the distance from the intercondylar axis to the most posterior point of the condyle.

MFC Distal / Posterior Offset Ratio

时间窗: Preoperative MRI

A unitless ratio calculated by dividing the medial femoral condyle distal offset distance by its posterior offset distance on sagittal MRI.

次要结局

  • Medial Joint Space Width (JSW)(Preoperative and minimum 24-month postoperative radiographs)
  • International Knee Documentation Committee (IKDC) Score(Preoperative and minimum 24-month postoperative follow-up)
  • Lysholm Knee Score(Preoperative and minimum 24-month postoperative follow-up)
  • Tegner Activity Scale(Preoperative and minimum 24-month postoperative follow-up)
  • Kellgren-Lawrence Grade Progression(Preoperative and minimum 24-month postoperative radiographs)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Fevzi Gurkan Aslan

Orthopaedic Surgery Resident, Department of Orthopaedics and Traumatology, Karadeniz Technical University Faculty of Medicine

Karadeniz Technical University

研究点 (1)

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