跳至主要内容
临床试验/NCT04871802
NCT04871802Unknown不适用

A Prospective, Randomized, Comparative Study in Two Groups to Assess the Effect of the Use of a Dietary Supplement Taxifolin Aqua on the Recovery Period After COVID Pneumonia and on the Biological Age

Pirogov Russian National Research Medical University2 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2021年5月10日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
100
试验地点
2
主要终点
Dynamics of ECHO CG

研究概览

简要总结

Objective of the study is to evaluate the effect of Taxifolin Aqua therapy on the indicators of respiratory function, the state of the arterial wall, the contractile function of the myocardium, as well as to assess the effect of Taxifolin Aqua therapy on markers of biological age, quality of patients life.

详细描述

The study will include 100 patients who had covid pneumonia 3 months ago. If the inclusion / exclusion criteria are met, the patient is asked to sign an informed consent to participate in the study. Consenting patients are randomized to an intervention group or a control group. The control group (n = 50) will receive standard therapy, patients from the intervention group (n = 50) will be prescribed Taxifolin Aqua 30 mg per day in addition to standard therapy. Patients will be randomized to the control and main group using random number spreadsheets, assuming that the control and main groups will be homogeneous in the main demographic and clinical parameters. Patient monitoring will be carried out within 2 months from the date of inclusion. A follow-up visit is scheduled in 2 months. During the study, the patient will be regularly monitored for tolerance and safety of therapy with Taxifolin Aqua.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Supportive Care
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients of both sexes who had covid pneumonia 3 months ago and signed an informed consent and aged 18+.

排除标准

  • Standard contraindications to Taxifolin Aqua use.

结局指标

主要结局

Dynamics of ECHO CG

时间窗: In 2 months after recruitment

ECHO CG

Dynamics of spirometry indices

时间窗: In 2 months after recruitment

spirometry

Dynamics of pulse wave velocity

时间窗: In 2 months after recruitment

applanation tonometry

Dynamics of augmentation index

时间窗: In 2 months after recruitment

applanation tonometry

次要结局

  • Dynamics of biological age(In 2 months after recruitment)

研究者

发起方
Pirogov Russian National Research Medical University
申办方类型
Other
责任方
Sponsor

研究点 (2)

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