JPRN-UMIN000011275已完成未知
Comparison of morning vs evening dosing of the latanoprost/timolol maleate fixed combination (Xalacom) on intraocular pressure control in primary open angle glaucoma. -Pilot Study - - Comparison of morning vs evening dosing of the latanoprost/timolol maleate fixed combination (Xalacom)
Department of Ophthalmology, Kanazawa University0 个研究点目标入组 40 人开始时间: 2013年7月25日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 75years-old（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •(1) Pregnant and lactating women, the women who desired of the pregnancy. (2) Patients who have difficulty or are unable to undergo fundoscopy (severe cataract, etc.). (3) Patients with active external ocular diseases, ocular inflammation or infection. (4) Patients with myopia of at least 9.0D spherical equivalent and more than hyperopia 9.0D spherical equivalent (5) Patients with anisometropia more than 3D spherical equivalent (6)Patients with any corneal abnormality or other condition preventing reliable applanation tonometry. (7) Patients with history of refractive surgery, glaucoma surgery (SLT, trabeculotomy, trabeculectomy etc), vitreous surgery or retinal detachment surgery. (8) Patients with history of surgery for cataract within 3 months before the study. (9)Patients expected to require operation for an eye disease during the study period. (10)Patients with serious renal impairment (nephrotic syndrome, acute renal failure, chronic renal failure, etc.) (11) Patients with hepatic function disorder. (12) Patients with bronchial asthma or its history. (13) Patients with bronchospasm or serious chronic obstructive pulmonary disease. (14) Patients with cardiac failure, sinus bradycardia, atrioventricular block (second and third degrees), or cardiogenic shock. (15) Patients with right cardiac failure due to pulmonary hypertension. (16) Patients with congestive cardiac failure. (17) Patients with diabetic ketoacidosis and/or metabolic acidosis. (18)Patients with poorly controlled diabetes mellitus. (19)Patients with a anamnestic history of hypersensitivity to any ingredients of the investigational product. (20) Patients who has received administration of the adrenocortical steroid agent (except for local skin administration other than around eyes). (21) Patients whom doctor judged to be ineligible for this study.
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