The Reliability and Validity of the L-test in Patients With Multiple Sclerosis
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Gazi University
- Enrollment
- 68
- Locations
- 1
- Primary Endpoint
- L test
Study Overview
Brief Summary
Walking safely inside or outside is an important function in patients with Multiple Sclerosis (PwMS) that affects their daily life activity and participation. Loss of functional mobility is the major component of walking disorders in PwMS. Therefore, it is important to evaluate functional mobility.
Many functional mobility tests have been used for PwMS; however, these tests generally focus on walking speed and endurance. On the other hand, the L test, a variation of the timed up and go test (TUG), is a functional mobility measurement tool that extends the total walking distance to 20 meters and also requires the patients to turn both clockwise and counterclockwise.
Although L the test is an easy-to-use, short-term test method that evaluates higher-level components of functional mobility such as turns and transfers, to our knowledge, no study has systematically examined the reliability and validity of the L test in PwMS yet. In addition, the cut-off times that best discriminate PwMS from healthy people and fallers with non-fallers with Multiple Sclerosis (MS) have not been reported. Therefore, this study planned to investigate the reliability, validity, and discrimination of the L test in PwMS.
Detailed Description
At baseline, the L test, Timed Up and Go test, 10 meter walk test, six minute walk test, and the timed 360 turn test will be applied to the Multiple Sclerosis group. The L test will be repeated after seven days after the first application in PwMS. Healthy controls are going to perform only the L test.
Study Design
- Study Type
- Observational
- Observational Model
- Other
- Time Perspective
- Cross Sectional
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Age at least 18 years,
- •Neurologist-diagnosed Multiple Sclerosis,
- •Expanded Disability Status Scale (EDSS) score between 0-5,
- •No MS exacerbation within the last 3 months,
- •Use of stable medication in the last 3 months.
Exclusion Criteria
- •Having any vision, hearing, or perception problems that may affect the research results,
- •Having an orthopedic problem that will prevent walking and standing
- •Having a cardiovascular, pulmonary, or hormonal disorder
Outcomes
Primary Outcomes
L test
Time Frame: baseline
The L test evaluates functional mobility. Higher durations indicate worse functional mobility performance.
L test-second assessment
Time Frame: the second assessment will be conducted after the seven days
The L test evaluates functional mobility. Higher durations indicate worse functional mobility performance.
Secondary Outcomes
- the timed 360° turn test(Baseline)
- 6 minute walk test(Baseline)
- Timed Up and Go test(Baseline)
- 10 meter walk test(Baseline)
Investigators
Kader Eldemir
Research Assistant
T.C. ORDU ÜNİVERSİTESİ