Evaluation of the Quality of Cardio-Pulmonary Resuscitation (CPR) in Cardiac Arrest Patients

Completed

• Conditions: Cardiac Arrest

• Registration Number: NCT00951704
• Lead Sponsor: Tampere University Hospital

Brief Summary

The prognosis of cardiac arrest patients is generally poor. Recent studies have showed that the high quality of CPR increases the survival after cardiac arrest. Therefore the investigators planned this prospective observational study to determine the epidemiology of sudden cardiac arrest in the prehospital setting of Tampere area, the quality of the CPR, and also the associations between depth and frequency of chest compressions and invasive arterial pressure, EtCO2,cerebral oxygenation and iatrogenic injuries associated to chest compressions 1) in patients resuscitated out of hospital by emergency medical service's (EMS's) personals and 2) in-hospital by hospital resuscitation team members. In addition, the investigators will analyze the effects of the chosen method of resuscitation on critical vital signs (Etco2 and invasive pressures): closed-chest CPR is compared to open-chest CPR, or mechanical CPR with a device (AutoPulse-CPR, Cardio Pump) compared to manual CPR guided with quality CPR device. The results will give the investigators important insights into the haemodynamics of CPR which may guide future strategies for the management of cardiac arrest. The research group is also interested in CPR related injuries and mattress effect. Quality of life after CA is evaluated among survivals and the cause of death among non-survivors.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-11
• Study First Submitted: 2009-07-31
• Study First Submitted QC: 2009-08-03
• Study First Posted: 2009-08-04
• Primary Completion: 2015-12
• Status Verified: 2018-12
• Study Completion: 2018-12
• Last Update Submitted: 2018-12-12
• Last Update Posted: 2018-12-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• cardiac arrest
• > 18 years of age

Exclusion Criteria

• < 18 years of age

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The success rate of current guidelines (depth and frequency of chest compression, epidemiology)	During the resuscitation
Quality of life after CA	6 months	Quality of life after CA is usually fairly good measurement of quality of resuscitation attempt

Secondary Outcome Measures

Name	Time	Method
Invasive arterial pressures, cerebral oxygenation (NIRS), EtCO2	During the resuscitation
survival of cardiac arrest	hospital discharge

Trial Locations

Locations (2)

Tampere University Hospital; 🇫🇮 Tampere, Pirkanmaa, Finland

Department of Anesthesiology and Intensive Care, Turku University Hospital; 🇫🇮 Turku, Finland