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Clinical Trials/NCT00951704
NCT00951704
Completed
Not Applicable

Evaluating the Quality of Prehospital and In-hospital Cardio-pulmonary Resuscitation - Comparing the Compressions to Concurrent Vital Signs (Invasive Blood Pressure, Cerebral Oxygen Saturation, EtCO2) and Iatrogenic Injuries Associated to Chest Compressions.

Tampere University Hospital2 sites in 1 country1,000 target enrollmentNovember 2008
ConditionsCardiac Arrest

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cardiac Arrest
Sponsor
Tampere University Hospital
Enrollment
1000
Locations
2
Primary Endpoint
The success rate of current guidelines (depth and frequency of chest compression, epidemiology)
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

The prognosis of cardiac arrest patients is generally poor. Recent studies have showed that the high quality of CPR increases the survival after cardiac arrest. Therefore the investigators planned this prospective observational study to determine the epidemiology of sudden cardiac arrest in the prehospital setting of Tampere area, the quality of the CPR, and also the associations between depth and frequency of chest compressions and invasive arterial pressure, EtCO2,cerebral oxygenation and iatrogenic injuries associated to chest compressions 1) in patients resuscitated out of hospital by emergency medical service's (EMS's) personals and 2) in-hospital by hospital resuscitation team members. In addition, the investigators will analyze the effects of the chosen method of resuscitation on critical vital signs (Etco2 and invasive pressures): closed-chest CPR is compared to open-chest CPR, or mechanical CPR with a device (AutoPulse-CPR, Cardio Pump) compared to manual CPR guided with quality CPR device. The results will give the investigators important insights into the haemodynamics of CPR which may guide future strategies for the management of cardiac arrest. The research group is also interested in CPR related injuries and mattress effect. Quality of life after CA is evaluated among survivals and the cause of death among non-survivors.

Registry
clinicaltrials.gov
Start Date
November 2008
End Date
December 2018
Last Updated
7 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • cardiac arrest
  • \> 18 years of age

Exclusion Criteria

  • \< 18 years of age

Outcomes

Primary Outcomes

The success rate of current guidelines (depth and frequency of chest compression, epidemiology)

Time Frame: During the resuscitation

Quality of life after CA

Time Frame: 6 months

Quality of life after CA is usually fairly good measurement of quality of resuscitation attempt

Secondary Outcomes

  • Invasive arterial pressures, cerebral oxygenation (NIRS), EtCO2(During the resuscitation)
  • survival of cardiac arrest(hospital discharge)

Study Sites (2)

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