Cognitive-Behavioural Therapy (CBT) for Adult Attention Deficit Hyperactivity Disorder (ADHD): a Randomised Controlled Trial

Not Applicable

Completed

• Conditions: Adult Attention Deficit Hyperactivity Disorder (ADHD); Other disorders of adult personality and behaviour; Mental and Behavioural Disorders

• Registration Number: ISRCTN03732556
• Lead Sponsor: South London and Maudsley NHS Foundation Trust (UK)

Brief Summary

1. 2014 protocol in: http://www.ncbi.nlm.nih.gov/pubmed/25207986 2. 2018 results in: https://www.ncbi.nlm.nih.gov/pubmed/29282731

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-11-04
• Study Completion: 2014-04-30
• Last Update Posted: 12 November 2018

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Current inclusion criteria as of 17/12/2012:
1. Men and women aged 18-65 with a diagnosis of adult ADHD according to NICE guidelines i.e. if there was evidence from both the participant and the informant (where available) that:
1.1. the participant met DSM-IV criteria for Adult ADHD both in childhood and adulthood
1.2. the participant experienced at least moderate psychological, social and/or educational or occupational impairment in multiple settings
1.3. symptoms occurred in two or more settings including social, familial, educational and/or occupational settings.
2. Participants will have received a diagnosis either from the Adult ADHD Service, Maudsley Hospital, London, UK or another specialist/secondary care service (in this case a copy of the diagnostic report will be required)
3. Participants will either already be attending follow-up clinics, including psychoeducation workshops, or will have been recently referred to the service for medication follow-up or psychological treatment
4. Currently score 6 or more on the inattentive or hyperactive/impulsive subscale of the Adult Barkley Current Behaviour Scale (self-rated)
5. Clinical severity of at least a moderate level (Clinical Global Impression score of 4 or above)

Previous inclusion criteria until 17/12/2012:
1. Men and women aged 18 to 65 who have received a diagnosis of adult ADHD in the Adult ADHD Service at the Maudsley Hospital, London, UK
2. Currently score 6 or more on the inattentive or hyperactive/impulsive subscale of the Adult Barkley Current Behaviour Scale (self-rated)
3. Clinical severity of at least a moderate level (Clinical Global Impression score of 4 or above)
4. If on medication to be on a stabilised dose as defined by no more than 10% change in medication dose over a two-month period

Exclusion Criteria

1. Clinically significant anxiety disorder
2. Current episode major depression, current suicidality or self-harm (score of moderate or high suicidality on the M.I.N.I.)
3. Acquired brain injury
4. Primary diagnosis of psychosis or bipolar disorder
5. Pervasive developmental disorder
6. Active substance misuse/dependence in last three months
7. Verbal IQ <80
8. Diagnosis of a personality disorder
9. Participant not willing to comply with the requirements of an RCT
10. If the assessor does not perceive ADHD to be the current primary problem

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Adult Barkley Current Behaviour Scale (Barkley 2006) <br>An 18-item self-report measure assessing ADHD symptoms, rated on a 4-point Likert scale<br>2. Work and Social Adjustment Scale (Mundt et al 2002) <br>A reliable and valid self-report measure of impaired functioning attributable to an identified problem, consisting of 5 items, each rated on an 8-point scale<br><br>All outcomes will be assessed at baseline, 30 and 42 weeks. There is an assessment at the 30-week point also in case of attrition and for further analyses, but 30-week measures will not be used as the main outcomes.