The effect of promethazine on reducing children's restlessness during eye examinations
Phase 3
Completed
- Conditions
- Restlessness of children during the examination.
- Registration Number
- IRCT20200406046969N1
- Lead Sponsor
- Zahedan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 62
Inclusion Criteria
Children 2 to 7 years
Satisfaction and willingness to cooperate with parents
Lack of history of seizures and current use of anticonvulsant drugs
Lack of liver disease (hepatitis)
Lack of coagulation problems
Exclusion Criteria
Parental unwillingness to study
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The amount of restlessness during eye examinations. Timepoint: 20 minutes after taking the drug. Method of measurement: Based on behavioral observation-researcher-made questionnaire.
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie promethazine's sedative effects in pediatric ophthalmic procedures?
How does promethazine compare to midazolam for sedation in children during eye trauma assessments?
Are there specific biomarkers that predict promethazine response in restless pediatric patients?
What are the potential adverse events associated with promethazine use in children and how are they managed?
What alternative antihistamines or combination therapies are being explored for pediatric procedural sedation in ophthalmology?