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Evaluation of a Microendoscopic Imaging System in Examination of Resected Tissues

Terminated
Conditions
Known or Suspected Dysplasia or Cancer
Registration Number
NCT01968863
Lead Sponsor
University of Arkansas
Brief Summary

The overall objective of this exploratory, laboratory study is to evaluate whether noninvasive fluorescence microendoscopic imaging of tissue can assist clinicians in detecting dysplastic (precancerous) areas during standard surveillance. This is a study designed to evaluate the feasibility of using prototype imaging technology to enhance the detection of precancerous changes in various tissues. The results of this laboratory study will be used to further develop the technology for clinical application.

The primary aim of this project will be to investigate what digital image analysis criteria can be used to best detect dysplasia in various types of resected tissue.

Detailed Description

Not available

Recruitment & Eligibility

Status
TERMINATED
Sex
All
Target Recruitment
13
Inclusion Criteria
  • Males and females over the age of 18 scheduled for standard of care resection of abnormal tissue
Exclusion Criteria
  • Previous chemotherapy or radiation treatment to the tissue to be resected
  • Inability to provide consent

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Statistical measurements of the spatial and intensity distributions of pixels within an imageUp to 24 hours

The statistical measurements will be used to correlate each microendoscope image to a histopathology diagnosis.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

University of Arkansas for Medical Sciences

🇺🇸

Little Rock, Arkansas, United States

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