Evaluation of a Microendoscopic Imaging System in Examination of Resected Tissues
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Known or Suspected Dysplasia or Cancer
- Sponsor
- University of Arkansas
- Enrollment
- 13
- Locations
- 1
- Primary Endpoint
- Statistical measurements of the spatial and intensity distributions of pixels within an image
- Status
- Terminated
- Last Updated
- 10 years ago
Overview
Brief Summary
The overall objective of this exploratory, laboratory study is to evaluate whether noninvasive fluorescence microendoscopic imaging of tissue can assist clinicians in detecting dysplastic (precancerous) areas during standard surveillance. This is a study designed to evaluate the feasibility of using prototype imaging technology to enhance the detection of precancerous changes in various tissues. The results of this laboratory study will be used to further develop the technology for clinical application.
The primary aim of this project will be to investigate what digital image analysis criteria can be used to best detect dysplasia in various types of resected tissue.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Males and females over the age of 18 scheduled for standard of care resection of abnormal tissue
Exclusion Criteria
- •Previous chemotherapy or radiation treatment to the tissue to be resected
- •Inability to provide consent
Outcomes
Primary Outcomes
Statistical measurements of the spatial and intensity distributions of pixels within an image
Time Frame: Up to 24 hours
The statistical measurements will be used to correlate each microendoscope image to a histopathology diagnosis.