CT av förkalkade kranskärl Med fotonräknarteknik
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 29
- 试验地点
- 1
- 主要终点
- Diagnostic accuracy of CT concerning coronary stenosis with conventional angiography as reference
研究概览
简要总结
Coronary CT angiography is challenging in patients with more than mildly calcified coronary vessels, because of calcium artefacts that prevents evaluation of the lumen. The purpose of the CCT-PCD-1-study is to evaluate the diagnostic accuracy and image quality in coronary CT angiography using a commercially available CT system equipped with a photon counting detector technology.
Patients referred for cardiac CT and conventional coronary angiography as part of routine preoperative evaluation before Transcatheter Aortic Valve Implantation (TAVI) will be asked for inclusion in the study. This group of patients has generally a coronary artery calcium burden and perform cardiac CT and coronary angiography as part of routine care.
The diagnostic accuracy concerning significant coronary artery stenosis on the preoperative CT will be evaluated with the conventional coronary angiography as reference. Also, CT examination image quality will be evaluated.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients referred for cardiac CT AND conventional coronary angiography as part of routine preoperative evaluation.
排除标准
- •<65 years old.
- •Heart arrhythmia.
- •Heart rate >90/min with contraindication against beta blockers.
- •Not capable of giving informed consent
- •eGFR <30 mL/min/1.73m2
结局指标
主要结局
Diagnostic accuracy of CT concerning coronary stenosis with conventional angiography as reference
时间窗: 1 day. (Coronary angiography is usually performed the same day as cardiac CT.)
Coronary angiography with or without FFR is performed as part of routine care for included patients. The outcome measure is the agreement between coronary CT and coronary angiography.
次要结局
- Image quality(1 day. (Image quality is assessed on the performed examination))