Impact of Type II Diabetes Mellitus on Basic Coagulation Profile and Platelet Indices in Non-dialysis Chronic Kidney Disease Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- Estimate risk of thrombosis or bleeding for the 3 study groups by partial thromboplastin time
研究概览
简要总结
To investigate the effect of co existance of diabetes mellitus and chronic kidney disease on basic coagulation profile in comparison with diabetic patients with normal kidney function and non diabetic patients with chronic kidney disease
详细描述
We will study impact of type 2 diabetes mellitus on basic coagulation profile and platelet indices among patients with chronic kidney disease
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with diabetes mellitus with and without chronic kidney disease Patients with chronic kidney disease without diabetes mellitus
排除标准
- •any situation influence on basic coagulation profile and platelet indices other than diabetes mellitus and chronic kidney disease
结局指标
主要结局
Estimate risk of thrombosis or bleeding for the 3 study groups by partial thromboplastin time
时间窗: 1 day
We will include 150 patients as previous Fourth measure is partial thromboplastin time
Estimate risk of thrombosis or bleeding for the 3 study groups by serum fibrinogen
时间窗: 1 day
We will include 150 patients as previous Fifth measure is serum fibrinogen level in the 3 groups
Estimate risk of thrombosis or bleeding for the 3 study groups by platelet distribution width
时间窗: 1 day
We will include 150 patients as previous Seventh measure is platelet distribution width for the 3 groups
Estimate risk of thrombosis or bleeding for the 3 study groups by prothrombin time
时间窗: 1 day
We will include 150 patients and classify them into 3 groups each one consists of 50 patients First group those patients with diabetes mellitus only Second group those patients with chronic kidney disease only Third group those patients with combined diabetes mellitus type 2 and chronic kidney disease not on hemodialysis First we will measure prothrombin time
Estimate risk of thrombosis or bleeding for the 3 study groups by plateletcrit
时间窗: 1 day
We will include 150 patients as previous Eighth measure is plateletcrit of the 3 study groups
Estimate risk of thrombosis or bleeding for the 3 study groups by prothrombin concentration
时间窗: 1 day
We will include 150 patients classified into 3 groups as previous Second measure is prothrombin concentration
Estimate risk of thrombosis or bleeding for the 3 study groups by INR
时间窗: 1 day
We will include 150 patients as previous Third measure is INR ( international normalised ratio )
Estimate risk of thrombosis or bleeding for the 3 study groups by mean platelet volume
时间窗: 1 day
We will include 150 patients as previous Sixth measure is mean platelet volume in the 3 groups
次要结局
未报告次要终点
研究者
Mohamed Khalaf Mohamed
Assistant lecturer
Sohag University