Tamponade vs Partial Myometrial Resection of Lower Uterine Segment in Management of Placenta Accreta Spectrum Cases
- Conditions
- Placenta Accreta
- Interventions
- Procedure: Tamponade of lower uterine segment in management of placenta accreta spectrum casesProcedure: partial myometrial resection of lower uterine segment in management of placenta accreta spectrum cases
- Registration Number
- NCT06575023
- Lead Sponsor
- Assiut University
- Brief Summary
To compare the efficacy of lower uterine tamponade and partial lower myometrial resection in the management of intraoperative bleeding in cases with placenta accreta spectrum .
- Detailed Description
Placenta accreta spectrum (PAS) represents the spectrum of clinical conditions when part or whole of the placenta becomes abnormally adherent or invades the myometrium (1-2). Over the last 40 years, caesarean delivery rates around the world have risen from less than 10% to over 30%, and almost simultaneously a 10-fold increase in the incidence of PAS (3). PAS is one of the most dangerous conditions of the pregnancy as it is significantly associated with maternal morbidity and mortality (4).
Ultrasound imaging is the most commonly used technique to diagnose PAS disorders prenatally. There is also wide variation globally on the management of PAS disorders, with some centres opting for a radical approach, whereas others have proposed a range of conservative approaches (5).
The conservative approaches include one-step conservative surgery, leaving the placenta in situ, the Triple-P procedure, and transverse B-Lynch suture (1). Several techniques have been described for controlling massive bleeding associated with placenta previa caesarean sections ,including uterine packing with gauze ,balloon tamponades ,the B-Lynch suture,insertion of parallel vertical compression sutures, a square suturing technique and embolization or ligation of the uterine and internal iliac arteries , but there is awide variation in the success rate of these maneuvers. Over-sewing of the bleeding site is the most common procedure used for PPH management, but in many cases, the bleeding points located in the lower segment and cervical canal are too deep and their locations are unclear because of the severity of the bleeding(
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- Female
- Target Recruitment
- 222
-
1-Pregnant women with placenta previa /PAS diagnosed before delivery (by ultrasound and Doppler examination) .
2 - Gestational age starting from 28 weeks onwards. 3- Women with at least 1 previous hysterotomy (e.g. Caesarean deliveries, myomectomy) 4- Elective or emergent Caesarean deliveries
- A pre-existing decision of performing intrapartum hysterectomy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description tamponade of lower uterine segmentin managment of placenta accreta spectrum cases Tamponade of lower uterine segment in management of placenta accreta spectrum cases usage of tamponade of the lower uterine segment in managment of placnta accreta spectrum cases partial myometrial resection of lower uterine segment in management of placenta accreta spectrum partial myometrial resection of lower uterine segment in management of placenta accreta spectrum cases partial resection of lower uterine segment myometrium
- Primary Outcome Measures
Name Time Method amount of intraopertive blood loss. 2 years compare of amount of blood loss between two methods by adding collected blood in suction apparatus in milliliters to amount of biood in the soaked towels
- Secondary Outcome Measures
Name Time Method blood transfusion 2 years amount of transfused blood units
drop of HB level postoperative 2 years result of substitution of HB level postoperative from preoperative in gmldl
ICU admission 2 years yes or no admission number of days if there is ICU admission cause of admission
Re exploration 2 years if there is exploration or no cause of re-exploration outcome of re-exploration