Clinical Utility of Computed Tomography Derived Extracellular Volume Fraction in Cardiovascular Disease: A Meta-analysis
Not Applicable
- Conditions
- Cardiovascular disease
- Registration Number
- JPRN-UMIN000049627
- Lead Sponsor
- Yokohama City University
- Brief Summary
Pooled CT-derived ECV values were 28.5% (95% CI: 27.3%-29.7%) in the control, 31.9 (95% CI: 30.2%-33.8%) in the aortic stenosis, and 48.9% (95% CI: 44.5%-53.3%) in the cardiac amyloidosis group. ECV was significantly elevated in aortic stenosis (P = 0.002; vs controls) but further elevated in cardiac amyloidosis (P < 0.001; vs aortic stenosis). CT-derived ECV had a high diagnostic accuracy for cardiac amyloidosis, with sensitivity of 92.8% (95% CI: 86.7%-96.2%), specificity of 84.8% (95% CI: 68.6%-93.4%).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 2545
Inclusion Criteria
Not provided
Exclusion Criteria
We will exclude references that are unbeatable for our analysis, such as those with missing data.
Study & Design
- Study Type
- Others,meta-analysis etc
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method