A Study of Pancreatectomy with Autologous Islet Transplantation for Treatment of Chronic Pancreatitis - Auto-I

Shimoda Masayuki0 个研究点目标入组 10 人开始时间: 2022年6月24日最近更新: 2023年10月17日

适应症

试验速览

暂无简介。

•1. A written consent can be obtained. 2. Age is between 18 and 70 years old. 3. Diagnosis of chronic pancreatitis or pancreatic arteriovenous malformation 4.Previous conservative treatment, celiac plexus block, endoscopic treatment or surgical treatment were ineffective.

•1. BW >100kg or BMI >30 kg/m2. 2. Insulin requirement >0.8IU/kg/day or >55U/day. 3. Type 1 diabetes. 4. HbA1c>10%. 5. Systolic blood pressure >160 mmHg or diastolic blood pressure >100 mmHg. 6. eGFR >30ml/min/1.73m2. 7. Pregnancy or breastfeeding. 8. Active infections, Hepatitis B, hepatitis C or mycobacteriosis including tuberculosis. 9. Malignant tumor. However, those who have been diagnosed as recurrence-free after treatment are not excluded. 10. Alcoholism or drug dependency 11. Hb<10 g/dL. However, this does not exclude cases where blood transfusion is planned during surgery. 12. Coagulopathy. 13. Severe heart disease. 14. Liver dysfunction. 15. Portal vein hypertension or liver fibrosis. 16. Pancreatic tumor. 17. Gastrointestinal disorders with impair oral drug absorption. 18. Participant in another clinical trial. 19. Patients who are unable to make regular outpatient visits. 20. Mental illness. 21. Patients who are judged to be inappropriate by clinical trial investigators.

发起方

Shimoda Masayuki