NCT00273494Unknown3 期
Scandinavian Neoadjuvant Phase III Study of Induction Chemotherapy Followed by Irradiation Alone or Surgery Plus Irradiation in NSCLC Stage IIIA/N2 (T1N2, T2N2, T3/N2).
适应症
试验速览
- 阶段
- 3 期
- 入组人数
- 406
- 试验地点
- 2
- 主要终点
- Survival
研究概览
简要总结
Hypothesis is that surgery is of benefit in locally advanced NSCLC with N2 disease.
Patients are randomised to surgery or not.
详细描述
Patients are after staging randomised to neoadj. chemotherapy followed by surgery followed by irradiation or to chemotherapy followed by irradiation.
Endpoint is survival.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Histologically verified NSCLC
- •Stage IIIA/N2
- •age 18-75
- •Lung function test allowing surgery
- •Mediastinoscopy performed
排除标准
- •Prior chemotherapy
- •Prior irradiation
结局指标
主要结局
Survival
次要结局
- time to progression
研究者
研究点 (2)
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