Effects of coffee drinking on glucose metabolism, cytokines and gastrointestinal hormone secretion: a single-blind randomised controlled trial

Physiologic Effects of Coffee Committee (PEC) (Netherlands)0 个研究点目标入组 49 人开始时间: 2009年7月3日最近更新: 2019年7月1日

适应症

试验速览

•For inclusion in this trial subjects must fulfill all of the following criteria:
•1. Written informed consent to participate in this trial
•2. All drugs which may interfere with glucose metabolism must be discontinued. These include all medication for diabetes, asthma, heart diseases and stomach. Regular non-steroidal anti-inflammatory drug (NSAID) use must also be discontinued.
•3. Men and women aged less than 65 years (no lower age limit)
•4. Normal fasting insulin level
•5. 13 points as a result in the diabetes risk score
•6. 7.0 - 12.0 mmol/l as 2-hour blood glucose value in the OGTT

•Any of the following is regarded as a criterion for exclusion from the trial:
•1. Deterioration any of base examination which reveal diabetic state
•2. Persons with previous diagnosis of diabetes mellitus
•3. Use of drugs, which interfere with glucose metabolism or receiving treatment to lower blood glucose
•4. Pregnant women and women who are breast feeding
•5. History of malignancy, which needs any therapeutic intervention
•6. History of any chronic diseases or other medical characteristics likely to interfere with participation in the study
•7. Subjects with imbalanced clinical conditions, such as thyroid and liver diseases, which could interfere with glucose metabolism
•8. History of alcohol or drug abuse, or both

发起方

Physiologic Effects of Coffee Committee (PEC) (Netherlands)