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Clinical Assessment of a Daily Disposable Soft Silicone Hydrogel Contact Lens

Not Applicable
Completed
Conditions
Refractive Errors
Interventions
Device: Delefilcon A contact lenses
Registration Number
NCT06044948
Lead Sponsor
Alcon Research
Brief Summary

The purpose of this study is to assess the clinical performance of DAILIES TOTAL1® spherical soft contact lenses over approximately 1 week of daily wear.

Detailed Description

Subjects will be expected to attend 2 visits (Visit 1 Screen/Baseline/ Dispense; and Visit 2 Week 1 Follow-up/ Exit). The total duration of a subject's participation in the study as well as exposure to the contact lenses will be approximately 1 week (6-8 days of contact lens wear).

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
97
Inclusion Criteria
  • Current wearer of commercial spherical soft contact lenses in both eyes with at least 3 months of wearing experience, with a minimum wearing time of 5 days per week and 10 hours per day;
  • Manifest cylinder less than or equal to 0.75 diopter (D) in each eye;
  • Best corrected distance visual acuity better than or equal to 20/25 (Snellen) in each eye.

Key

Exclusion Criteria
  • Current or prior habitual DAILIES TOTAL1 soft contact lens wear in the past 3 months prior to consent;
  • Monovision contact lens wear;
  • Wearing habitual contact lenses in an extended wear modality (routinely sleeping in lenses for at least 1 night per week) over the last 3 months prior to enrollment.

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
DAILIES TOTAL1Delefilcon A contact lensesDelefilcon A contact lenses worn in both eyes for the typical number of hours the subject wears his/her habitual contact lenses. The lenses will be worn in a daily disposable manner.
Primary Outcome Measures
NameTimeMethod
Distance VA With Study Lenses at Week 1Week 1

Visual acuity (VA) was measured for each eye individually with study lenses on eye using letter charts. VA was recorded in Snellen where 20/20 represents normal distance eyesight and 20/15 represents better than normal eyesight. No hypothesis testing was prespecified for this endpoint.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (6)

Optometry Group, PLLC

🇺🇸

Memphis, Tennessee, United States

Tallahassee Eye Center

🇺🇸

Tallahassee, Florida, United States

The Eye Doctors, Inc.

🇺🇸

Eden Prairie, Minnesota, United States

Oculus Research, Inc.

🇺🇸

Garner, North Carolina, United States

ProCare Vision Center

🇺🇸

Granville, Ohio, United States

Wyomissing Optometric Center

🇺🇸

Wyomissing, Pennsylvania, United States

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