P53 Immunohistochemistry Abnormal Staining in Endometrial Cancer

Completed

• Conditions: Endometrial Cancer

• Registration Number: NCT05542940
• Lead Sponsor: Hossam Hassan Aly Hassan El Sokkary

Brief Summary

Objective: Calculate the incidence of P53 immunohistochemistry abnormal staining in endometrial cancer and to identify its relation with disease stages, pathological types and grading.

Patients and methods:

100 cases of endometrial cancer will be included in the study, recruited from Alexandria university hospital gyne-oncology unit. Surgical staging, histopathological examination and immunohistochemistry of p53 were done to all cases to calculate the incidence of P53 immunohistochemistry abnormal staining in endometrial cancer and to identify its relation with disease stages, pathological types, grading.

Keywords: P53 immunohistochemistry, endometrial cancer, clinicopathological relation.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-01-01
• Primary Completion: 2022-08-31
• Study Completion: 2022-08-31
• Status Verified: 2022-09
• Study First Submitted: 2022-09-08
• Study First Submitted QC: 2022-09-13
• Last Update Submitted: 2022-09-13
• Study First Posted: 2022-09-16
• Last Update Posted: 2022-09-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

• endometrial cancer patients

Exclusion Criteria

• patients unfit for surgery

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
p53 immunohistochemistry	1 month	Incidence of abnormal staining of p53 in endometrial cancer
Relation of p53 abnormal staining with disease stages	1month	Relation of p53 abnormal staining with disease stages
Relation of p53 abnormal staining with disease pathological types	1 month	Relation of p53 abnormal staining with disease pathological types
Relation of p53 abnormal staining with disease pathological grades	1 month	Relation of p53 abnormal staining with disease pathological grades

Trial Locations

Locations (1)

Hossam Hassan El Sokkary; 🇪🇬 Alexandria, Egypt