Skip to main content
Clinical Trials/NCT05420428
NCT05420428
Completed
Not Applicable

Applying High Resolution Impedance Manometry for Perioperative Swallowing Changes in Older Patients Receiving Endotracheal Intubation or Supraglottic Airway Devices During Orthopedic Surgery: a Pilot Randomized Controlled Trial

National Taiwan University Hospital1 site in 1 country32 target enrollmentJune 21, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Hypopharyngeal Mean Pressure
Sponsor
National Taiwan University Hospital
Enrollment
32
Locations
1
Primary Endpoint
hypopharyngeal mean peak pressure
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

We aimed to investigate whether patients with tracheal intubation has high hypopharyngeal pressure than patients with supraglottic airway does by using high resolution impedance manometry. We expected that the patients with endotracheal intubation have higher hypopharyngeal pressure than the patients with supraglottic airway devices.

Detailed Description

Background: More and more older patients required to receive orthopedic surgery recently. The intubation or supraglottic airway device are required to maintain airway during general anesthesia. Previous studies only reported the subjective swallowing discomfort feeling, however, the objective data was limited. The high-resolution impedance manometry could detect the swallowing muscle power changes with multiple pressure sensors and impedance channels. Objectives: we aimed to investigate whether patients with tracheal intubation has high hypopharyngeal pressure than patients with supraglottic airway does Patients and methods: The patients receive orthopedic surgery with older than 60 years old. They received high resolution impedance manometry examination at preoperative day, in the post-anesthetic care unit, postoperative day 3 to 7 (pick a day) along with subjective questionnaires. We also followed the IDDSI guideline to test different viscosity of the patients' tolerance for food. Expected result: The patients with endotracheal intubation have higher hypopharyngeal pressure than the patients with supraglottic airway devices.

Registry
clinicaltrials.gov
Start Date
June 21, 2022
End Date
December 4, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • The patients receive orthopedic surgery with older than 60 years old including 60 years old.

Exclusion Criteria

  • The patients had severe major organ dysfunction

Outcomes

Primary Outcomes

hypopharyngeal mean peak pressure

Time Frame: 15 minutes

hypopharyngeal pressure during food bolus transmittion

Study Sites (1)

Loading locations...

Similar Trials