Evaluation of the peripheral circulation and vascular reactivity in patients with different degrees of cirrhosis

• Conditions: microcirculation; peripheral circulation; cirrhosis; 10019654

• Registration Number: NL-OMON30284
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

Cirrhosis Child-Pugh B and C.

Exclusion Criteria

Patients with one of the following non-cirrhotic diseases: arterial hypertension, diabetes mellitus, and peripheral vascular disease.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Vascular reactivity as measured by changes in PFI and NIRS in a human reactive<br /><br>hyperaemia model.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Peripheral perfusion as measured by PFI and OPS; peripheral tissue oxygenation<br /><br>as measured by NIRS. </p><br>