NCT03805256Unknown不适用
Preoperative and Postoperative ctDNA Comparison in Early Stage Lung Cancer
Second Affiliated Hospital of Soochow University1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2018年5月14日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- The potential value of ctDNA in the diagnosis of NSCLC
研究概览
简要总结
Mutation-positive peripheral blood ctDNA became mutation-negative after surgical removal of the cancer tissue. All subjects in the control group were negative for ctDNA mutations。
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with pulmonary nodules who underwent curative-intent resection were able to enter the study -
排除标准
- •Patients who received any invasive examination or treatment prior to resection or had a history of malignancy; patients who do not attend follow up after surgery; blood samples that were contaminated; and biopsies that exhibited advanced lung cancer in pathology。
结局指标
主要结局
The potential value of ctDNA in the diagnosis of NSCLC
时间窗: Half a year
The sensitivity,specificity,positive predictive valueand the negative predictive value of mutations in plasma ctDNA for detecting early-stage lung cancer
次要结局
未报告次要终点
研究者
研究点 (1)
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