Detection of pseudoprogression using CT perfusion in patients with Glioblastoma Multiforme post-treatment

Completed

• Conditions: Glioblastoma Multiforme; Cancer

• Registration Number: ISRCTN68166254
• Lead Sponsor: The Walton Centre NHS Foundation Trust

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-07-01
• Study Completion: 2016-03-01
• Last Update Posted: 2 July 2018

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

1. Patients with glioblastoma multiforme tumours who will be discussed in the regional neuro-oncology multidisciplinary team meeting
2. Patients exhibiting any tumour progression on their first follow-up imaging immediately after radiotherapy, surgery or chemotherapy post-treatment without clinical progression

Exclusion Criteria

Patients who exhibit tumour progression both clinically (symptoms) and on imaging on the first follow-up imaging immediately following radiotherapy, chemotherapy or surgery following treatment

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Diagnosis of true tumour progression measured by MRI scan 8 weeks after treatment

Secondary Outcome Measures

Name	Time	Method
Better diagnosis and improved treatment options