Prognostic Factors Influencing the Recurrence Rate and Survival of Patients With Colorectal Cancer: a Single Institution Experience
- Conditions
- Colorectal Cancer
- Registration Number
- NCT06325410
- Lead Sponsor
- Zagazig University
- Brief Summary
over the past decade colon cancer has emerged as the second most deadly and the third most common type of cancer in the world with increasing incidence in Egypt due to life style and diet change. some research showed relation between colon cancer recurrence and advanced tumor staging. To investigators knowledge, this is the first time to be done in Zagazig University.
Data was collected from records in a retrospective cohort study
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 200
- Adult patients with newly diagnosed colorectal cancer
- Age > 18 years old
- recurrent cases of colorectal cancer
- Pediartric patient less than 18 yr
- In operable or metastatic cancer colon
- No other malignancies
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method site of recurrence through study completion, an average of 5 years site of tumor recurrence was detected
age through study completion, an average of 5 years age of patients was obtained from medical records
sex through study completion, an average of 5 years sex of patients was obtained from medical records
tumor grade through study completion, an average of 5 years tumor grade after resection from pathology report recorded
tumor site through study completion, an average of 5 years tumor site recorded from operative findings
post operative complications through study completion, an average of 5 years from records; if there were post operative complication like fecal fistula
medical disease through study completion, an average of 5 years co-existing medical disease was obtained from medical records
occupation through study completion, an average of 5 years occupation of the patient at time of surgery and if it was changed
previous surgery through study completion, an average of 5 years previous surgical history was obtained from medical records
CEA through study completion, an average of 5 years value of carcino-embryonic antigen was recorded
tumor size through study completion, an average of 5 years tumor size was measured by length x width in cm from records
neoadjuvant therapy through study completion, an average of 5 years history of neoadjuvant therapy before surgery from records obtained
hand sewen or stappled anastmosis through study completion, an average of 5 years if there was bowel re-anastmosis after surgery, it was done using a stappler or hand sewing sutures. this was obtained from operative data in patient records
surgical margins of resected tumor through study completion, an average of 5 years safety margins were assessed from pathological examination under microscopy and recorded in pathology reports, it can be free surgical margins ( no tumor cells) or positive surgical margins( presence of tumor cells)
adjuvant therapy through study completion, an average of 5 years history of adjuvant therapy post operative obtained from records
diet through study completion, an average of 5 years diet and dietary life style from history
family history through study completion, an average of 5 years history taking of family history of cancer disease
soiling by during surgery through study completion, an average of 5 years by history from records if there was soiling of the field by tumor cells
type of surgery(laparoscopic or open) through study completion, an average of 5 years type of operation was laparoscopic or open surgery obtained from records
type of resected tumor through study completion, an average of 5 years type of tumor was recorded from pathology reports
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Zagazig University Hospitals
🇪🇬Zagazig, Egypt