Comparison of various parameters of PRBCs prepared by two different methods of leukoreduction.
Not Applicable
Completed
- Registration Number
- CTRI/2021/06/034330
- Lead Sponsor
- Institute of Liver and Biliary Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
1. PRBC units prepared from whole blood units collected as per donor eligibility criteria laid by drugs and cosmetics act as a part of quality control.
2. PRBC units leukoreduced by leukofiltration only.
3. PRBC units leukoreduced by buffy coat removal followed by leukofiltration.
Exclusion Criteria
1. Transfusion Transmitted Infections reactive ( HIV Ag/Ab, HBsAg, anti HCV, Malarial Parasite, VDRL ) whole blood units.
2. Whole blood units failing routine quality control inspection like under collected, over collected, hemolyzed and lipemic units.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Residual leukocyte count per unit will be assessed in the packed red blood cells unitTimepoint: 1. Baseline leukocyte count will be assessed after collection of whole blood. <br/ ><br>2. Residual leukocyte count per unit after leukoreduction of the packed red blood cells. <br/ ><br>3. Residual leukocyte count at 42 days of storage <br/ ><br>
- Secondary Outcome Measures
Name Time Method Percentage hemolysis will be assessed in the leukoreduced packed red cells unit.Timepoint: 1. After leukoreduction at the time of processing of the packed red blood cells unit. <br/ ><br>2. At 42 days of storage of packed red blood cells unit