The effect of nicotine on Parkinson's disease.
Phase 3
Recruiting
- Conditions
- Parkinson's disease.Parkinson's disease
- Registration Number
- IRCT20210618051612N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 45
Inclusion Criteria
Parkinson's patients who have been diagnosed with Parkinson's disease according to the MDS clinical diagnostic criteria for Parkinson's disease
Age over 50 years old
Patients receiving dopaminergic therapy who have reached a stable dose to control symptoms
Patients who have signed the consent form
Exclusion Criteria
Severe systemic or psychological disease
History of gastrointestinal bleeding
Taking aspirin with a dose of more than 325 mg per day
Taking drugs that increase insulin sensitivity, heparin, warfarin or other anticoagulants and antiplatelets
Exposure to cigarette smoke
Alcohol consumption
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Evaluation of disease severity from the Unified Parkinson's Disease Rating Scale (UPDRS). Timepoint: At the beginning and end of the study. Method of measurement: Evaluation of disease severity from the Unified Parkinson's Disease Rating Scale (UPDRS).
- Secondary Outcome Measures
Name Time Method