Microbiome in Active and Sedentary Older People

CSIRO Health and Biosecurity0 个研究点目标入组 86 人开始时间: 2019年2月5日最近更新: 2021年10月11日

试验速览

暂无简介。

•Male or female individuals
•- Aged 65 years to 80 years of age, inclusive
•- BMI 20 to 30 kg/m2, inclusive
•- Understand the study requirements, willing and able to undertake all study assessments over three separate visits and provide written informed consent
•- Score equal to or greater than 26 on the Montreal Cognitive Assessment
•- Score of either sedentary (equal to or less than 200 METs/week) or active (equal to or greater than 1000 METs/week) as assessed using the Global Physical Activity Questionnaire (GPAQ)

•- History of smoking within the last 6 months
•- Living in a care facility or retirement home that has communally prepared meals
•- Surgical history that in the opinion of the Principal Investigator could modulate gut function (e.g. - gastric bypass, colectomy etc.)
•- Use of medication/nutraceuticals within the last 3 months that in the opinion of the Principal Investigator may interfere with colonic microbiome composition (e.g. – antibiotics, steroids, laxatives, fibre supplements, probiotic/prebiotic supplements etc.)
•- Self-reported history of diabetes, gastrointestinal, renal, hepatic disease or intestinal inflammation, including inflammatory bowel disease (Crohn’s disease and ulcerative colitis), coeliac disease, short bowel syndrome, irritable bowel syndrome, chronic constipation or regular bouts of diarrhoea, cancer or stroke, within the last 5 years
•- Self-reported psychological/psychiatric disorder (e.g. depression, anxiety etc.) that in the opinion of a Psychologist might impact the participant’s ability to undertake study measurements
•- Self-reported history of claustrophobia
•- Presence of any ferrous metal in the body
•- Self-reported alcohol consumption of equal to or greater than 14 standard drinks per week
•- Self-reported participation in a study with any experimental drug/supplement within the 30 days prior to commencement of the study

发起方

CSIRO Health and Biosecurity