Functional Electrical Stimulation of Peripheral Muscles in Heart Failure With Preserved Left Ventricular Ejection Fraction

Attikon Hospital1 site in 1 country30 target enrollmentJanuary 2011

ConditionsHeart Failure With Preserved Left Ventricular Ejection Fraction

Overview

Phase: Phase 2
Intervention: Not specified
Conditions: Heart Failure With Preserved Left Ventricular Ejection Fraction
Sponsor: Attikon Hospital
Enrollment: 30
Locations: 1
Primary Endpoint: Exercise capacity
Status: Completed
Last Updated: 13 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to evaluate the effects of functional electrical stimulation of peripheral muscles on clinical and emotional status, endothelial function and left ventricular diastolic function in heart failure with preserved left ventricular ejection fraction.

Registry

clinicaltrials.gov

Start Date

January 2011

End Date

October 2012

Last Updated

13 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Attikon Hospital

Responsible Party

Principal Investigator

John Parissis

Assistant Professor of Cardiology

Attikon Hospital

Eligibility Criteria

Inclusion Criteria

•(i) symptoms \[New York Heart Association (NYHA) class II or III\] and signs typical of heart failure
•(ii) left ventricular (LV) ejection fraction (LVEF) \>50% and LV end-diastolic volume index \<97 mL/m2
•(iii) findings of left atrial (LA) dilatation (LA volume index \>40mL/m2), LV hypertrophy and/or LV diastolic dysfunction \[ie, mitral E/A ratio \<1 or \>2, mitral E/e' ratio \>15 or 8-15, (A pulmonary - A mitral) duration difference \>30 ms etc)
•(iv) no alterations in medical therapy during the previous 4 weeks
•(v) no myocardial infarction within 3 months prior to enrollment