Structural and Functional Left Ventricular Remodelling in Patients With Obstructive Sleep Apnea
Not Applicable
Completed
- Conditions
- Obstructive Sleep Apnea
- Registration Number
- NCT00768807
- Lead Sponsor
- Associação Fundo de Incentivo à Pesquisa
- Brief Summary
The purpose of this study is to determine whether patients with obstructive sleep apnea have any changes in left ventricular function and structure after 06 months of continuous positive airway pressure treatment.
- Detailed Description
Several studies have been suggesting that Obstructive Sleep Apnea contributes to deterioration of left ventricular diastolic function. It may be associated to increased risk of cardiovascular events. We hypothesized that morphological and functional left ventricular changes might be reverted after treatment with Continuous positive airway pressure.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 450
Inclusion Criteria
- Apnea-hypopnea index higher than 5 events per hour
Exclusion Criteria
- Body mass index higher than 40 kg/m2
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Improvement of left ventricular diastolic echo variable 06 months
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Instituto do Sono/AFIP
🇧🇷Sao Paulo, Brazil
Instituto do Sono/AFIP🇧🇷Sao Paulo, Brazil