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临床试验/NCT01400529
NCT01400529已完成不适用

Etude 3000 ARTHROSES Symptomatic Knee and Hip Osteoarthritis Prevalence Survey. Programme de Recherche du Groupe Qualité de Vie, de la Section Epidémiologie et de la Section Arthrose de la Société Française de Rhumatologie

Central Hospital, Nancy, France6 个研究点 分布在 1 个国家目标入组 3,000 人开始时间: 2007年3月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
3,000
试验地点
6

研究概览

简要总结

Nationwide descriptive epidemiology survey aiming to determine lower limb OA prevalence, based on a validated method previously used to assess inflammatory rheumatism (rheumatoid arthritis and spondylarthropathy) prevalence in France.

详细描述

Osteoarthritis (OA) is a degenerative disease progressively affecting joint cartilage and subchondral bone, leading to pain, limited range of motion and functional impairment. Knee and hip are the more frequently affected joints. There is no treatment able to cure OA or at least to slow down cartilage damage. Thus, when symptomatic treatments become ineffective, joint prosthetic replacement is the unique solution.

There is a substantial lack of information about osteoarthritis (OA) epidemiology in France, as well as in other European countries, which becomes more and more critical with population aging. The need for additional knowledge was outlined in the law about public health priorities in France, published on August 9th, 2004. In this document, a specific call is made for additional investigation on functional limitations, disability and quality of life modification of people affected by OA.

Up to now, available information is mainly limited to short- or medium-term studies, conducted in clinic-based samples. Thus, based on demography and public health conclusions, implementing population-based epidemiologic studies is required in order to improve scientific knowledge with regards to :

  • prevalence of symptomatic OA,
  • its natural history over years and potential prognostic factors influencing the disease,
  • its impact in terms of quality of life changes, disability, lack of autonomy and health resource use.

Our expert group, which has a substantial experience in osteoarthritis, epidemiology and health service research, has developed a 2-part research program aiming to help answering to OA-related public health questions:

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Cross Sectional

入排标准

年龄范围
40 Months 至 75 Years(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • age 40-75
  • adults in households representative of the French population for age, sex, area of living and number of household members.

排除标准

  • 未提供

研究者

发起方
Central Hospital, Nancy, France
申办方类型
Other

研究点 (6)

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