Onderzoek naar nieuwe diagnostische markers voor vroeg-diagnostiek van necrotiserende enterocolitis bij pasgeborenen.
Completed
- Conditions
- ecrotizing enterocolitis (NL: necrotiserende enterocolitis)acute abdomen in neonates (NL: neonaten met acute buik)
- Registration Number
- NL-OMON26582
- Lead Sponsor
- MC Groningen
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
Patients in the neonatal intensive care unit with (suspected) NEC (Bell's stage 1 or higher).
Exclusion Criteria
1. Congenital bowel defects;
2. Intensive light therapy for hyperbilirubinaemia necessitating the use for three phototherapy lamps.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Urinary I-FABP/claudine to creatinine ratio;<br /><br>2. Tissue oxygenation as measured by NIRS.
- Secondary Outcome Measures
Name Time Method Inflammatory/metabolic markers (such as WBC, CRP, TNFa, pH value, lactate and interleukines).