Short-term-effects of wearing an unloader brace on muscle activity, knee kinematics, acoustic emissions and kinetics during selected movements in persons with medial knee osteoarthritis: a hybrid design placebo-controlled trial

Not Applicable

Conditions: M17.4
M17.0
M17.1
M17.3
Primary gonarthrosis, bilateral
Other primary gonarthrosis
Other secondary gonarthrosis, bilateral
Other post-traumatic gonarthrosis

Registration Number: DRKS00025739

Lead Sponsor: Abteilung Sportmedizin, Goethe-Universität Frankfurt am Main

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: All

Target Recruitment: 113

Inclusion Criteria

1.Medial (varus) osteoarthritis Kellgren-Lawrence grade II to IV (lateral osteoarthritis & PF osteoarthritis: 0-I°), primarily one knee
3.Current (day maximum) knee pain of >30 mm on a 0-100 mm VAS scale during motion
4.Varus knee alignment 2 – 10°
5.BMI < 35 kg/m2

Exclusion Criteria

1.Ligament instability, knee flexion contracture > 15° (compared to the contralateral knee), overall limited mobility (Charnley class C)
2.History of knee, tibial or femoral surgery or fracture, history of hip or ankle joint osteoarthritis
3.Current musculoskeletal injuries/complaints except unilateral knee osteoarthritis
4.Cardiovascular / neurologic diseases or impairments / diabetes / rheumatoid, inflammatory , or neuropathic arthritis
5.History of previous large radiation exposure
6.Current pregnancy
7.Knee injection within the previous 12 months.
8. Septic arthritis, bone metabolic disease

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Knee joint acoustic emissions. Assessed by means of two high-performance, low power, top port silicon microphones with a diameter of 3 cm and a depth of 1 cm (SPU0414HR5H-SB; Knowles Electronics, LLC. Itasca, IL, USA). Outcomes: Amplitude and Mean power frequency.

Secondary Outcome Measures