A Prospective cross-over randomized controlled trial of protein bound uremic toxin reduction between super high-flux hemodialysis and high-efficiency online hemodiafiltratio
Phase 3
Completed
- Conditions
- albumin lost in dialysate fluid
- Registration Number
- TCTR20181019001
- Lead Sponsor
- ipro, Japan
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 12
Inclusion Criteria
•Age between 18 to 90 year-old
•ESRD on HD at least 3 months
•HD at least 3 times per week and spKt/v > 1.2
•Residual renal function < 100 ml
•AVF or AVG that BFR more than 400 ml/min
•Appropriated dry weight by BCM
•Hemodynamic stability
Exclusion Criteria
•Uncorrected heart disease and severe infection
•Advance malignancy
•Cirrhosis Child Pugh score B to C
•Pregnancy
•Contraindication for anticoagulant
•refuse inform consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Indoxyl sulphate reduction ratio end of the study percentage
- Secondary Outcome Measures
Name Time Method beta2 microglobulin reduction ratio end of the study percentage