Skip to main content
MedPathMedPath Home
Clinical Trials/ISRCTN76193287
ISRCTN76193287
Active, not recruiting
Phase 4

A Study of Cardiovascular Events iN Diabetes Plus (ASCEND PLUS)

niversity of Oxford0 sites20,000 target enrollmentJune 27, 2022
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit

Overview

Phase
Phase 4
Intervention
Not specified
Conditions
Not specified
Sponsor
niversity of Oxford
Enrollment
20000
Status
Active, not recruiting
Last Updated
3 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
June 27, 2022
End Date
August 17, 2048
Last Updated
3 years ago
Study Type
Interventional
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • •1\. Adults aged at least 55 years
  • •2\. Type 2 diabetes mellitus

Exclusion Criteria

  • •1\. Myocardial Infarction
  • •3\. Current or planned treatment with a GLP\-1 RA
  • •4\. Previous hypersensitivity to or intolerance of GLP\-1 RA therapy
  • •5\. Severe hypoglycaemia within the last six months or during run\-in
  • •6\. Symptomatic hypoglycaemia within the last month
  • •7\. Currently under consideration to commence insulin
  • •8\. Severe heart failure (NYHA class 4\)
  • •9\. Current or planned renal replacement therapy
  • •10\. Unwilling to complete regular follow\-up assessments
  • •11\. Ongoing treatment for cancer or diagnosis with cancer (excluding non\-melanoma skin cancer) in the last 2 years

Outcomes

Primary Outcomes

Not specified

Similar Trials

Not yet recruiting
Not Applicable
Study on complications of diabetes and risk of heart attack
CTRI/2019/01/017120Osmania Medical College
Active, not recruiting
Not Applicable
Diabetes and vascular complications: the role of endothelin and physical inactivity’
EUCTR2009-015602-18-NLActelion Pharmaceuticals
Completed
Not Applicable
*Diabetes and vascular complications: normoxia versus hypoxia*diabetes mellitus type 210018424
NL-OMON35263niversitair Medisch Centrum Sint Radboud20
Not yet recruiting
Not Applicable
Occurrence of heart related risk factors in Diabetes mellitusHealth Condition 1: E115- Type 2 diabetes mellitus with circulatory complications
CTRI/2020/03/023738Department Of Physiotherapy
Completed
Not Applicable
Microvascular complications of diabetes mellitusmicrovascular complications in patients with diabetes type 1 and 2E14.3
DRKS00007880niversitätsklinikum Heidelberg, Klinik für Endokrinologie, Stoffwechsel und Klinische Chemie502