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临床试验/EUCTR2006-000612-24-GB
EUCTR2006-000612-24-GB进行中(未招募)1 期

Trial of Aciclovir Prophylaxis of Herpes Infections in Critical Care - TRAPHICC

Greater Glasgow Health Board (North Glasgow University Hospitals Division)0 个研究点目标入组 500 人开始时间: 2006年2月20日最近更新:
适应症
相关药物

试验速览

阶段
1 期
状态
进行中(未招募)
发起方
入组人数
500

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional clinical trial of medicinal product

入排标准

入选标准

  • All patients (over 18 years) entering ICU provided
  • 1. Patient expected to stay in the ICU longer than 36 hours and with an endotracheal or tracheostomy tube inserted within 24 hours of admission to the ICU.
  • 2. Patient does not require treatment with Aciclovir, Valaciclovir, Ganciclovir, Foscarnet, Probenicid or other drug known to have anti herpes simplex activity
  • 3.Patient does not have a known allergy to Aciclovir.
  • 4.Females of childbearing age must have negative pregnancy test on admission
  • 5.Written informed consent from the patient or assent obtained from relatives.
  • Are the trial subjects under 18? no
  • Number of subjects for this age range:
  • F.1.2 Adults (18-64 years) yes
  • F.1.2.1 Number of subjects for this age range
  • F.1.3 Elderly (>=65 years) yes
  • F.1.3.1 Number of subjects for this age range

排除标准

  • a)Duration of admission confidently expected to be less than 36 hours
  • b)Patient has clinical features of HSV disease
  • c)Patient previously randomised to this study.
  • d)Patients deemed to be suitable for entry to another trial
  • e)Previous hypersensitivity to aciclovir or Valaciclovir
  • f)Patient requiring agent with anti herpes virus activity
  • g)Patient previously enrolled in another trial of an investigational drug within the past 30 days
  • h)Patient is pregnant or lactating
  • j) Patient with endotracheal or tracheostomy in place for more than 24 hours before admission to ICU.

研究者

发起方
Greater Glasgow Health Board (North Glasgow University Hospitals Division)

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