Efficacy of sivelestat sodium administration in perioperative care of abdominal aortic aneurysm with pulmonary function disorder
Phase 2
- Conditions
- abdominal aortic aneurysm
- Registration Number
- JPRN-UMIN000000650
- Lead Sponsor
- Keio University, School of Medicine Department of Surgery
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Not provided
Exclusion Criteria
Cases matching following conditions are excluded from the trial. (1)Patients allergic to the components of sivelestat sodium. (2)Patients who are pregnant, have a possibility of pregnancy, and breast-feeding. (3)Patients with evidence of high left atrium pressure. (4)Cases that are considered not eligible for the trial by the doctor in charge. (5)Patients without pulmonary function disorder, meaning patients with the P/F ratio of more than 300 and the chest X-ray that does not show bilateral infiltration shadow during the operation.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method incidence of postoperative complications, lung injury score, duration of SIRS
- Secondary Outcome Measures
Name Time Method mortality rate, in-hospital days, period in ICU, mechanical ventilation period, each cytokines