3R Rehabilitation Management of COVID-19 Survivors
- Conditions
- Covid19
- Interventions
- Other: Cardiopulmonary exercise (centre-based)Other: Cardiopulmonary exercise (online-based)
- Registration Number
- NCT04892979
- Lead Sponsor
- The Hong Kong Polytechnic University
- Brief Summary
It is to explore the temporal relationships between physical fitness, cognitive, psychosocial functions, and health-related quality of life (HRQoL) in COVID-19 survivors over the first 15 months; and to determine the effects of centre-based (CBR), online-based cardiopulmonary rehabilitation (OBR), and combined centre- and online-based rehabilitation (COBR) on survivors with initially suboptimal pulmonary functions.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 400
- COVID survivor at hospital discharge or 6-month post-disease onset
- Medically stable with an Abbreviated Mental Test (AMT) scores of > 6 out of 10
- Having contraindications to exercise
- Physical Activity Readiness Questionnaire (PAR-Q) reveals unsafety
- Cannot understand Cantonese
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Combined Cardiopulmonary exercise (centre-based) Combined centre- and online-based exercise cardiopulmonary rehabilitation program for 6 weeks Combined Cardiopulmonary exercise (online-based) Combined centre- and online-based exercise cardiopulmonary rehabilitation program for 6 weeks Centre-based Cardiopulmonary exercise (centre-based) Centre-based exercise cardiopulmonary rehabilitation program for 6 weeks Online-based Cardiopulmonary exercise (online-based) Online-based exercise cardiopulmonary rehabilitation program for 6 weeks
- Primary Outcome Measures
Name Time Method Fatigue measured by Fatigue Assessment Scale Baseline The Fatigue Assessment Scale is a 10-item scale evaluating symptoms of chronic fatigue.exercise test.
- Secondary Outcome Measures
Name Time Method Muscle strength by 30-second double-leg sit-to-stand test (times) 6 weeks after the start of intervention Muscle strength will be assessed with the 30-second double-leg sit-to-stand test. If the participant can perform the 30-second single leg sit-to-stand test with pain or difficulty, they will be invited to complete 30-second single-leg sit-to-stand test. The number of completed repetitions will be counted.
Self-efficacy by 6-Item Chronic Disease Self-Efficacy scale 6 weeks after the start of intervention A six-item digital self-administered self-efficacy questionnaire will be used to evaluate patients' confidence in performing exercise, managing their own symptoms and emotions and completing their daily tasks.
Self-perceived quality of life by The St. George's Respiratory Questionnaire-HK version 6 weeks after the start of intervention The St. George's Respiratory Questionnaire-HK version is a self-reported questionnaire. This 50-item disease specific questionnaire assesses 3 domains (symptoms, activity, and impacts).
Self-perceived quality of life by The Hong Kong Chinese version Short Form-36 6 weeks after the start of intervention The Hong Kong Chinese version Short Form-36 is a concise 36-item health status questionnaire with good psychometric properties.
Cardiac output (L/min) 6 weeks after the start of intervention Non-invasive electrodes will be placed on the clavicle and lateral side of chest wall by a non-invasive measurement of cardiac output using the CardioScreen 1000 System. Non-invasive electrodes will be placed on the clavicle and lateral side of chest wall bilaterally
Cardiac stroke volume (ml/m2) 6 weeks after the start of intervention Non-invasive electrodes will be placed on the clavicle and lateral side of chest wall by a non-invasive measurement of cardiac output using the CardioScreen 1000 System. Non-invasive electrodes will be placed on the clavicle and lateral side of chest wall bilaterally
Forced expiratory volume in one second (l) 6 weeks after the start of intervention FEV1 is the volume of air that can forcibly be blown out in first 1 second, after full inspiration
Forced vital capacity (l) 6 weeks after the start of intervention Forced vital capacity (FVC) is the volume of air that can forcibly be blown out after full inspiration
FEV1/FVC 6 weeks after the start of intervention Ratio of forced expiratory volume in one second and forced vital capacity
Peak expiratory flow rate (l/s) 6 weeks after the start of intervention Peak expiratory flow (PEF) is the maximal flow (or speed) achieved during the maximally forced expiration initiated at full inspiration
Exercise capacity (m) 6 weeks after the start of intervention Exercise capacity will be assessed by the 6-minute walk test (6MWT), a submaximal exercise test.
Trial Locations
- Locations (4)
Princess Margaret Hospital
ðŸ‡ðŸ‡°Hong Kong, Hong Kong
Tuen Mun Hospital
ðŸ‡ðŸ‡°Hong Kong, Hong Kong
Pamela Youde Eastern Hospital
ðŸ‡ðŸ‡°Hong Kong, Hong Kong
Queen Elizabeth Hospital
ðŸ‡ðŸ‡°Hong Kong, Hong Kong