3R Rehabilitation Management of COVID-19 Survivors Using Centre-based and Online-based Approaches
Trial Snapshot
- Phase
- Not Applicable
- Enrollment
- 400
- Locations
- 4
- Primary Endpoint
- Fatigue measured by Fatigue Assessment Scale
Study Overview
Brief Summary
It is to explore the temporal relationships between physical fitness, cognitive, psychosocial functions, and health-related quality of life (HRQoL) in COVID-19 survivors over the first 15 months; and to determine the effects of centre-based (CBR), online-based cardiopulmonary rehabilitation (OBR), and combined centre- and online-based rehabilitation (COBR) on survivors with initially suboptimal pulmonary functions.
Study Design
- Study Type
- Interventional
- Allocation
- Non Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •COVID survivor at hospital discharge or 6-month post-disease onset
- •Medically stable with an Abbreviated Mental Test (AMT) scores of > 6 out of 10
Exclusion Criteria
- •Having contraindications to exercise
- •Physical Activity Readiness Questionnaire (PAR-Q) reveals unsafety
- •Cannot understand Cantonese
Arms & Interventions
Centre-based
Centre-based exercise cardiopulmonary rehabilitation program for 6 weeks
Intervention: Cardiopulmonary exercise (centre-based) (Other)
Online-based
Online-based exercise cardiopulmonary rehabilitation program for 6 weeks
Intervention: Cardiopulmonary exercise (online-based) (Other)
Combined
Combined centre- and online-based exercise cardiopulmonary rehabilitation program for 6 weeks
Intervention: Cardiopulmonary exercise (online-based) (Other)
Combined
Combined centre- and online-based exercise cardiopulmonary rehabilitation program for 6 weeks
Intervention: Cardiopulmonary exercise (centre-based) (Other)
Outcomes
Primary Outcomes
Fatigue measured by Fatigue Assessment Scale
Time Frame: Baseline
The Fatigue Assessment Scale is a 10-item scale evaluating symptoms of chronic fatigue.exercise test.
Fatigue measured by Fatigue Assessment Scale
Time Frame: 6 weeks after the start of intervention
The Fatigue Assessment Scale is a 10-item scale evaluating symptoms of chronic fatigue.exercise test.
Secondary Outcomes
- Self-efficacy by 6-Item Chronic Disease Self-Efficacy scale(6 weeks after the start of intervention)
- Muscle strength by 30-second double-leg sit-to-stand test (times)(6 weeks after the start of intervention)
- Self-perceived quality of life by The St. George's Respiratory Questionnaire-HK version(6 weeks after the start of intervention)
- Self-perceived quality of life by The Hong Kong Chinese version Short Form-36(6 weeks after the start of intervention)
- Cardiac output (L/min)(6 weeks after the start of intervention)
- Cardiac stroke volume (ml/m2)(6 weeks after the start of intervention)
- Forced expiratory volume in one second (l)(6 weeks after the start of intervention)
- Forced vital capacity (l)(6 weeks after the start of intervention)
- FEV1/FVC(6 weeks after the start of intervention)
- Peak expiratory flow rate (l/s)(6 weeks after the start of intervention)
- Exercise capacity (m)(6 weeks after the start of intervention)
- Muscle strength by 30-second double-leg sit-to-stand test (times)(Baseline)
- Self-efficacy by 6-Item Chronic Disease Self-Efficacy scale(Baseline)
- Self-perceived quality of life by The St. George's Respiratory Questionnaire-HK version(Baseline)
- Self-perceived quality of life by The Hong Kong Chinese version Short Form-36(Baseline)
- Cardiac output (L/min)(Baseline)
- Cardiac stroke volume (ml/m2)(Baseline)
- Forced expiratory volume in one second (l)(Baseline)
- Forced vital capacity (l)(Baseline)
- FEV1/FVC(Baseline)
- Peak expiratory flow rate (l/s)(Baseline)
- Exercise capacity (m)(Baseline)