Punctal Cautery in Dry Eye Syndrome

Phase 3

• Conditions: Health Condition 1: O- Medical and SurgicalHealth Condition 2: H578- Other specified disorders of eye and adnexa

• Registration Number: CTRI/2024/05/067575
• Lead Sponsor: V Prasad Eye Institute

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 27 May 2024

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1. Aged 5–70 years

2. Have OSDI scores =33 or Oxford staining grade =2

3. Diagnosis of DED in both eyes supported by the criteria mentioned below

a.A symptom severity score of =33 for OSDI

b.An unanesthetized Schirmer Tear Test (STT) score of =1 mm and =5 mm per 5 minutes

c.Evidence of ocular surface staining (total fluorescein staining score of at least 3) [0-15 scale])

4. Have normal lid anatomy and diagnosed with severe dry eye (ATDDE)

5. DED refractory to medical management

Exclusion Criteria

1.History of punctal occlusion or punctal dilation.

2.Active ocular infection or inflammation.

3.Use of punctal plugs within the past 3 months.

4.Pregnancy or lactation women.

5.Any systemic or ocular condition that may interfere with the study assessments or participant safety.

6.Punctal plug or contact lenses.

7.Ocular surgery within 6 months.

Have no contraindication for blood donation

8.Positive HIV, hepatitis B or C, or syphilis.

Study & Design

• Study Type: Interventional
• Study Design: Not specified