The Effect of Obesity on Growth Hormone Response to Anaerobic Exercise

• Conditions: Obesity

• Registration Number: NCT01070589
• Lead Sponsor: Meir Medical Center

Brief Summary

The aim of the present study is to asses the effect of obesity on anaerobic exercise's growth hormone (GH) response.

Detailed Description

Exercise is a potent physiological stimulator of growth hormone (GH) release. GH is an important factor in the distribution of fat and lean tissue in the body. Previous studies suggested that the GH response to aerobic exercise may be attenuated by obesity. The effect of obesity on GH response to anaerobic effort is unclear. The aim of the present study is to asses the effect of obesity on anaerobic exercise's GH response. We will recruit 12 obese (BMI \> 30) healthy adults and 12 age and gender matched normal weight (BMI \< 25) controls. All the participants will conduct a "wingate" anaerobic test (30 seconds of intense effort against resistance calculated by the individual's body weight). Blood sample for GH level will be collected at 5 different time (0, 20, 30, 40 and 60 minutes after the test). We will compare the GH response in the two groups.

Study Timeline

• Study Start: 2010-02
• Study First Submitted: 2010-02-17
• Study First Submitted QC: 2010-02-17
• Study First Posted: 2010-02-18
• Status Verified: 2012-03
• Last Update Submitted: 2012-03-16
• Last Update Posted: 2012-03-19
• Primary Completion: 2012-07
• Study Completion: 2012-07

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 24

Inclusion Criteria

• Healthy female
• Age 18-40

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Exclusion Criteria

• Male
• Age <18, >40
• Heart, Liver, Kidney or Hypophyseal disease
• Medications that may alter GH secretion (eg Steroids, Eltroxin)

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Meir Medical Center; 🇮🇱 Kfar Saba, Israel