NL-OMON28811已完成4 期
ewborns with congenital diaphragmatic hernia: inhaled nitric oxide versus intravenous sildenafil: an international randomized controlled trial
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- Erasmus MC
- 入组人数
- 330
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 0 至 0（—）
入选标准
- •Diagnosis of CDH and pulmonary hypertension defined as 2 of the following 4 criteria:
- •I. Systolic PAP> 2/3 systemic systolic pressure estimated by echocardiography
排除标准
- •Severe chromosomal anomaly, like trisomy 18 or trisomy 13, which may imply a decision to stop or not to start life-saving medical treatment Severe cardiac anomaly, expected to need corrective surgery in the first 60 days of life (such as transposition of the great arteries, truncus arteriosus, coarctation aortae or double outlet right ventricle)
- •Renal anomalies associated with oligohydramnios Severe orthopaedic and skeletal deformities, which are likely to influence thoracic, and / or lung development (such as chest wall deformities and spine anomalies)
研究者
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