Oral Sodium Blood Pressure in Normal Weight, Overweight and Obese Volunteers

Phase 2

Completed

• Conditions: Obesity
• Interventions: Other: sodium chloride; Other: Methylcellulose crystalline

• Registration Number: NCT01532401
• Lead Sponsor: Poitiers University Hospital

Brief Summary

The primary objective of this study is to analyze the sensitivity of blood pressure to oral salt intake. Matched male and female participants will be selected as normal weight, overweight, and obese.

Participating subjects will have a first visit with blood pressure measurement and a blood sample. In two consecutive phases of one week, subjects will receive 12 pills of sodium (6 grams) or corresponding placebo. Blood pressure will be measured at the end of each phase.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-03
• Status Verified: 2012-02
• Study First Submitted: 2012-02-09
• Study First Submitted QC: 2012-02-13
• Study First Posted: 2012-02-14
• Primary Completion: 2014-09
• Last Update Submitted: 2016-10-10
• Last Update Posted: 2016-10-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 51

Inclusion Criteria

• Informed consent
• Age 18-45 for adults and 6-8 for children

Exclusion Criteria

• African ethnicity (known to affect blood pressure sensitivity to salt)
• Chronic condition affecting blood pressure
• Diabetes (known to affect blood pressure sensitivity to salt)
• Hypertension

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
chlorure de sodium	sodium chloride	-
Methylcellulose	Methylcellulose crystalline	-

Trial Locations

Locations (1)

Poitiers University Hospital; 🇫🇷 Poitiers, France