Pneumoperitoneum and Trendelenburg Position on Fluid Responsiveness

Completed

• Conditions: Fluid Responsiveness
• Interventions: Other: Ringer Lactate

• Registration Number: NCT04060069
• Lead Sponsor: Kocaeli University

Brief Summary

The increased intraabdominal pressure and intrathoracic pressure due to pneumoperitoneum negatively affect the cardiovascular system, relatively dynamic parameters may vary due to intraoperative fluid therapy.

Detailed Description

After the general anaesthesia induction and intubation, dynamic parameters such as SVV and PPV were monitored by pulse contour analysis.

Study Timeline

• Study Start: 2016-10-01
• Primary Completion: 2017-06-01
• Study Completion: 2017-07-01
• Status Verified: 2019-08
• Study First Submitted: 2019-08-09
• Study First Submitted QC: 2019-08-15
• Last Update Submitted: 2019-08-15
• Study First Posted: 2019-08-16
• Last Update Posted: 2019-08-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 45

Inclusion Criteria

• Age>18 years old patients
• Will undergo elective laparoscopic gynecological surgery
• ASA I-II

Exclusion Criteria

• Obese patients (body mass index> 30 kg.m2)
• Patients who had arrhythmia
• Patients who had cardiac insufficiency.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Before pneumoperitoneum	Ringer Lactate	Fluid administration

Primary Outcome Measures

Name	Time	Method
to evaluate how stroke volume variation (%) affected during the Trendelenburg position and pneumoperitoneum	up to 10 months	to evaluate reliability of stroke volume variation in evaluating the response to fluid administration
to evaluate how pulse pressure variation (%) affected during the Trendelenburg position and pneumoperitoneum	up to 10 months	to evaluate reliability of pulse pressure variation in evaluating the response to fluid administration