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Clinical Trials/NCT04060069
NCT04060069
Completed
Not Applicable

Influence of Pneumoperitoneum and Trendelenburg Position on Fluid Responsiveness Predicted by Pulse Pressure Variation and Stroke Volume Variation During Anaesthesia for Laparoscopic Gynaecological Surgery

Kocaeli University0 sites45 target enrollmentOctober 1, 2016

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Fluid Responsiveness
Sponsor
Kocaeli University
Enrollment
45
Primary Endpoint
to evaluate how stroke volume variation (%) affected during the Trendelenburg position and pneumoperitoneum
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

The increased intraabdominal pressure and intrathoracic pressure due to pneumoperitoneum negatively affect the cardiovascular system, relatively dynamic parameters may vary due to intraoperative fluid therapy.

Detailed Description

After the general anaesthesia induction and intubation, dynamic parameters such as SVV and PPV were monitored by pulse contour analysis.

Registry
clinicaltrials.gov
Start Date
October 1, 2016
End Date
July 1, 2017
Last Updated
6 years ago
Study Type
Observational
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Tulay Sahin

Clinical Professor

Kocaeli University

Eligibility Criteria

Inclusion Criteria

  • Age\>18 years old patients
  • Will undergo elective laparoscopic gynecological surgery

Exclusion Criteria

  • Obese patients (body mass index\> 30 kg.m2)
  • Patients who had arrhythmia
  • Patients who had cardiac insufficiency.

Outcomes

Primary Outcomes

to evaluate how stroke volume variation (%) affected during the Trendelenburg position and pneumoperitoneum

Time Frame: up to 10 months

to evaluate reliability of stroke volume variation in evaluating the response to fluid administration

to evaluate how pulse pressure variation (%) affected during the Trendelenburg position and pneumoperitoneum

Time Frame: up to 10 months

to evaluate reliability of pulse pressure variation in evaluating the response to fluid administration

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