Influence of Pneumoperitoneum and Trendelenburg Position on Fluid Responsiveness Predicted by Pulse Pressure Variation and Stroke Volume Variation During Anaesthesia for Laparoscopic Gynaecological Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 45
- 主要终点
- to evaluate how stroke volume variation (%) affected during the Trendelenburg position and pneumoperitoneum
研究概览
简要总结
The increased intraabdominal pressure and intrathoracic pressure due to pneumoperitoneum negatively affect the cardiovascular system, relatively dynamic parameters may vary due to intraoperative fluid therapy.
详细描述
After the general anaesthesia induction and intubation, dynamic parameters such as SVV and PPV were monitored by pulse contour analysis.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Age>18 years old patients
- •Will undergo elective laparoscopic gynecological surgery
排除标准
- •Obese patients (body mass index> 30 kg.m2)
- •Patients who had arrhythmia
- •Patients who had cardiac insufficiency.
结局指标
主要结局
to evaluate how stroke volume variation (%) affected during the Trendelenburg position and pneumoperitoneum
时间窗: up to 10 months
to evaluate reliability of stroke volume variation in evaluating the response to fluid administration
to evaluate how pulse pressure variation (%) affected during the Trendelenburg position and pneumoperitoneum
时间窗: up to 10 months
to evaluate reliability of pulse pressure variation in evaluating the response to fluid administration
次要结局
未报告次要终点
研究者
Tulay Sahin
Clinical Professor
Kocaeli University