临床试验/NCT01151748

NCT01151748撤回2 期

Intra-arterial Chemotherapy for Advanced Intraocular Retinoblastoma

Stanford University1 个研究点分布在 1 个国家开始时间: 2010年9月1日最近更新: 2012年5月14日

适应症

试验速览

阶段: 2 期
状态: 撤回
发起方: Stanford University
试验地点: 1
主要终点: Response: Globe salvage rate (Eyes saved/Eyes treated). This will be determined by clinical ocular examination.

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

Phase II study of selective intra-arterial infusion of chemotherapy for intraocular retinoblastoma

研究设计

研究类型: Interventional
分配方式: Non Randomized
干预模型: Single Group
主要目的: Treatment
盲法: None

入排标准

年龄范围: — 至 18 Years（Child, Adult）
性别: All
接受健康志愿者: 否

入选标准

•Patients diagnosed with advanced intraocular retinoblastoma (International Retinoblastoma Classification group D or E*).
•Patients with tumor recurrence or vitreous seeding following completion of systemic chemotherapy or previous radiation therapy.

排除标准

•Congenital brain anomaly identified on MRI.
•History of systemic coagulopathy.
•Evidence of extra ocular retinoblastoma on clinical examination or neuroimaging.

结局指标

主要结局

Response: Globe salvage rate (Eyes saved/Eyes treated). This will be determined by clinical ocular examination.

时间窗: Follow-up will be performed for one year from treatment date.

次要结局

未报告次要终点

研究者

发起方

Stanford University

申办方类型

Other

责任方

Sponsor

研究点 (1)

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