Metabolism in Psychiatry 3 - Predicting weight gain and therapy response in unipolar depressio

• Conditions: F32; F33; Depressive episode; Recurrent depressive disorder

• Registration Number: DRKS00025946
• Lead Sponsor: Klinikum der Universität München, Campus Großhadern

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-08-17
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 250

Inclusion Criteria

diagnosis of a current depressive episode (ICD-10: F32.x) or recurrent depression (ICD-10: F33.x)
- male and female psychiatric inpatients aged between 18 and 70 years
- ability to sufficiently speak and comprehend the German language
- continuing or beginning antidepressant drug regimen within two weeks after admission
- MADRS score = 14
- capability of providing written informed consent or in agreement with a legal representative.

Exclusion Criteria

- cognitive disability impeding completion of self-rating questionnaires or answering questions reasonably;
- presence of psychotic features, manic episode, bipolar disorder, disorders from the schizophreniform spectrum, eating disorder, drug or alcohol addiction. Other disorders (e.g. adjustment disorder, obsessive compulsive disorder, anxiety disorder, somatoform disorder, personality disorder) in case the symptoms predominate the clinical picture;
- presence of uncontrolled systemic disease, uncontrolled somatic (other than metabolic or cardiovascular disturbances) / neurological disorder (apart from migraine), current or recent (last month) severe infections or inflammatory disease, current or recent (last month) physical trauma;
- treatment with ECT;
- patients with immediate risk for suicidal behavior;
- pregnant, breast-feeding, or postmenopausal women.

Study & Design

• Study Type: observational
• Study Design: Not specified