IRCT20180818040827N2招募中未知
Evaluation of the effect of synbiotic supplementation on antioxidant and inflammatory markers, serum zonulin level and quality of life in patients with Parkinson's disease
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 入组人数
- 80
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 50 years 至 80 years（—）
- 性别
- All
入选标准
- •Patients who agree to participate in the study
- •Diagnosis of Parkinson's by a neurologist based on the diagnostic criteria of the Parkinson's Disease Association (UK Parkinson's disease society Brain Bank criteria)
- •Age 50 to 80 years
排除标准
- •Regular consumption of products fortified with probiotics and prebiotics, probiotic and prebiotics supplements at least 2 months before start of the study
- •Take antibiotics or laxatives at least 2 months before the start of the study
- •Take antioxidant supplements or supplements that affect the disease
- •Having a history of gastrointestinal surgery
- •History of chronic gastrointestinal disease, hypothyroidism or hyperthyroidism, severe psychosis, or other concomitant neurological diseases, cognitive impairment, smoking or nicotine or alcohol use
- •Having a history of type 1 and 2 diabetes
- •Taking anti-inflammatory and immunosuppressive drugs
- •Sensitivity to the compounds in the supplement
- •Having hoehn and yahr score of 5 out of 5
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