IRCT20180818040827N2
Recruiting
未知
Evaluation of the effect of synbiotic supplementation on antioxidant and inflammatory markers, serum zonulin level and quality of life in patients with Parkinson's disease
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Esfahan University of Medical Sciences
- Enrollment
- 80
- Status
- Recruiting
- Last Updated
- 5 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients who agree to participate in the study
- •Diagnosis of Parkinson's by a neurologist based on the diagnostic criteria of the Parkinson's Disease Association (UK Parkinson's disease society Brain Bank criteria)
- •Age 50 to 80 years
Exclusion Criteria
- •Regular consumption of products fortified with probiotics and prebiotics, probiotic and prebiotics supplements at least 2 months before start of the study
- •Take antibiotics or laxatives at least 2 months before the start of the study
- •Take antioxidant supplements or supplements that affect the disease
- •Having a history of gastrointestinal surgery
- •History of chronic gastrointestinal disease, hypothyroidism or hyperthyroidism, severe psychosis, or other concomitant neurological diseases, cognitive impairment, smoking or nicotine or alcohol use
- •Having a history of type 1 and 2 diabetes
- •Taking anti\-inflammatory and immunosuppressive drugs
- •Sensitivity to the compounds in the supplement
- •Having hoehn and yahr score of 5 out of 5
Outcomes
Primary Outcomes
Not specified
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