The effect of synbiotic supplementation on Parkinson's disease
- Conditions
- Parkinson's disease.Parkinson's disease
- Registration Number
- IRCT20180818040827N2
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 80
Patients who agree to participate in the study
Diagnosis of Parkinson's by a neurologist based on the diagnostic criteria of the Parkinson's Disease Association (UK Parkinson's disease society Brain Bank criteria)
Age 50 to 80 years
Regular consumption of products fortified with probiotics and prebiotics, probiotic and prebiotics supplements at least 2 months before start of the study
Take antibiotics or laxatives at least 2 months before the start of the study
Take antioxidant supplements or supplements that affect the disease
Having a history of gastrointestinal surgery
History of chronic gastrointestinal disease, hypothyroidism or hyperthyroidism, severe psychosis, or other concomitant neurological diseases, cognitive impairment, smoking or nicotine or alcohol use
Having a history of type 1 and 2 diabetes
Taking anti-inflammatory and immunosuppressive drugs
Sensitivity to the compounds in the supplement
Having hoehn and yahr score of 5 out of 5
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method