Pilot study to assess the effect of Brazil nuts on plasma selenium levels in healthy male volunteers aged 65 years and over
Not Applicable
Not yet recruiting
- Conditions
- Healthy male volunteers aged 65 years and older. The health condition for which the intervention may be indicated is prostate cancer.Cancer - Prostate
- Registration Number
- ACTRN12614001092684
- Lead Sponsor
- The University of Queensland
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not yet recruiting
- Sex
- Male
- Target Recruitment
- 30
Inclusion Criteria
Eligible participants include healthy, non-smoking men aged 65 years and older
Exclusion Criteria
Ineligible participants include the presence of nut-allergies and the regular use of a selenium supplement and not willing to discontinue use during the research study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The change in mean selenium response from baseline to 30 days[A blood sample (60 mL of whole blood) will be collected on 3 occasions: at baseline (day 0), midpoint (day 15) and endpoint (day 30) of the intervention. Plasma selenium levels will be assessed.]
- Secondary Outcome Measures
Name Time Method utritional biomarkers: plasma and whole blood GPx [The primary outcome blood sample will also be used to measure the secondary outcomes. A blood sample (60 mL of whole blood) will be collected on 3 occasions: at baseline (day 0), midpoint (day 15) and endpoint (day 30) of the intervention.];Selenoprotein P<br>[The primary outcome blood sample will also be used to measure the secondary outcomes. A blood sample (60 mL of whole blood) will be collected on 3 occasions: at baseline (day 0), midpoint (day 15) and endpoint (day 30) of the intervention.];Inflammatory marker: C-reactive protein (CRP)[The primary outcome blood sample will also be used to measure the secondary outcomes. A blood sample (60 mL of whole blood) will be collected on 3 occasions: at baseline (day 0), midpoint (day 15) and endpoint (day 30) of the intervention.]