Post treatment cervical intraepithelial neoplasia: randomised controlled trial using high-risk human papilloma virus testing for prediction of recurrent or residual disease
Completed
- Conditions
- Post treatment CIN, cytology, high-risk HPV testingCancerCervical intraepithelial neoplasia
- Registration Number
- ISRCTN31244687
- Lead Sponsor
- Erasmus Medical Centre (The Netherlands)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 204
Inclusion Criteria
Women indicated to be treated for high-grade CIN lesions.
Exclusion Criteria
1. Previous treatment for high-grade CIN
2. An immune compromised state
3. Previous or current cancer
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The reduction in the number of false-positives achieved by combined testing, through increasing the specificity of testing with unaltered sensitivity, resulting in fewer diagnostic procedures.
- Secondary Outcome Measures
Name Time Method 1. A decrease in unnecessary examinations and treatment<br>2. Possible influence of high-risk HPV genotyping and effects on health-costs