Lung Ultrasound for the Detection of Pulmonary Atelectasis in the Perioperative Period

Active, not recruiting

• Conditions: Postoperative Pulmonary Atelectases
• Interventions: Device: Ultrasound of the lungs; Device: Electric impedance tomography

• Registration Number: NCT02121275
• Lead Sponsor: Medical University of Vienna

Brief Summary

Atelectases (collapsed lung areas) of 15-20% of total lung occur in up to 90% of patients who are anaesthetized and intubated. The goal of the present prospective study is to detect atelectatic areas in the perioperative period in the lungs of patients undergoing elective laparoscopic surgery non-invasively and without x-ray exposure. Results of lung ultrasound (LUS) as the experimental method will be compared to the results of Electrical Impedance Tomography (EIT) as the reference technique for the detection of atelectasis. A device for peripheral Oxygen saturation measurement (MASIMO Radical-8) will detect changes in ventilation. The investigators want to confirm or disprove former findings of the appearance of intraoperative atelectases and to prove that ultrasound is a valid tool for detection of atelectases.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-09-06
• Study First Submitted: 2014-04-02
• Study First Submitted QC: 2014-04-21
• Study First Posted: 2014-04-23
• Primary Completion: 2016-06-30
• Status Verified: 2022-12
• Last Update Submitted: 2022-12-31
• Last Update Posted: 2023-01-04
• Study Completion: 2023-06

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

• Male or female,
• age 18 - 75
• BMI < 30
• Laparoscopic operation

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Exclusion Criteria

• Pregnancy
• Pulmonary infection
• Chronic pulmonary diseases
• Morbid Obesity

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Laparoscopic surgery	Ultrasound of the lungs	Patients undergoing laparoscopic surgery under general anaesthesia, patients undergo ultrasound of the lungs and electric impedance tomography at 4 times during anaesthesia
Laparoscopic surgery	Electric impedance tomography	Patients undergoing laparoscopic surgery under general anaesthesia, patients undergo ultrasound of the lungs and electric impedance tomography at 4 times during anaesthesia

Primary Outcome Measures

Name	Time	Method
Correlation between evidence of atelectasis in lung ultrasound and evidence of atelectasis in electric impedance tomography	on the day of laparoscopic surgery, expected average 2 hours in total	Measurements, requiring 5 minutes each, are performed before induction of anaesthesia, after intubation, immediately before extubation and immediately after extubation. Outcome measure: comparison of how often atelectases are detected by lung ultrasound (experimental method) versus by electric impedance tomography (standard method)

Secondary Outcome Measures

Name	Time	Method
respiratory variability of oxygen saturation	on the day of laparoscopic surgery, expected average 2 hours in total	from induction of anaesthesia until extubation

Trial Locations

Locations (1)

Medical University of Vienna, Dept. of Anesthesiology and General Intensive Care; 🇦🇹 Vienna, Austria