Risk markers, predictors and mechanisms of psychotherapy in social anxiety disorder

Not Applicable

Recruiting

• Conditions: F40.1; Social phobias

• Registration Number: DRKS00030701
• Lead Sponsor: niversitätsklinikum Freiburg, Klinik für Psychiatrie und Psychotherapie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-02-15
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 360

Inclusion Criteria

Primary diagnosis of social anxiety disorder (intervention/waitlist control groups only), Caucasian ancestry and German language proficiency.

Exclusion Criteria

Exclusion criteria for patients with social phobia are any comorbid bipolar or schizophrenic/psychotic disorders, autism, substance dependence (except nicotine), acute suicidality, severe neurological and/or somatic disease, illegal drug use, pregnancy, breast-feeding, impaired 3D vision, use of epigenetically active substances, general medical contraindications, or concomitant psychotherapy.
The exclusion criteria for the healthy control group are the same as those described above. In addition, the presence of a current or lifetime mental disorder according to DSM-5 (SCID-5-CV; First et al., 2016), excessive alcohol (more than 14 glasses/week), cigarette (more than 20 cigarettes/day), and caffeine consumption (more than 4 cups/day), or use of psychoactive medications will lead to exclusion from the study.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Decrease in social phobia symptoms, measured by psychometric diagnostics (e.g. Liebowitz Social Anxiety Scale)

Secondary Outcome Measures

Name	Time	Method
Changes in behavioral, physiological, neurobiological, molecular biological and immunological measures.